Full Form of 4KT

What is 4KT Full Form?

4KT is full form 4 (forever) K (killing) T (them)

What is 4 (forever) K (killing) T (them)?

CD4+ T cells help B cells to produce antibodies and help CD8+ T cells to kill virus-infected cells
One of the dominant cytokines produced by T cells is interferon gamma, a key player in controlling viral infection

Lymphopenia is a main feature of COVID-19 infection, affecting CD4+ T cells, CD8+ T cells, and B cells, and is more pronounced in severely ill patients

T cell responses in severely ill patients may be impaired, over-activated, or inappropriate, and further research is required to elucidate this and inform treatment strategies

There is some evidence of cross-reactivity with seasonal/endemic coronaviruses

Emerging studies suggest that all or a majority of people with COVID-19 develop a strong and broad T cell response, both CD4 and CD8, and some have a memory phenotype, which bodes well for potential longer-term immunity

Understanding the roles of different subsets of T cells in protection or pathogenesis is crucial for preventing and treating COVID-19